Endocrine Abstracts

A 56 year old female presents with the rare association of primary hyperaldosteronism with primary hyperparathyroidism and prolactinoma. The association of primary hyperaldosteronism and other endocrinopathies has only rarely been reported. There have been three case reports meeting diagnostic criteria for MEN 1 with aldosterone secreting adrenal adenomas. In all three the other endocrinopathies were pituitary adenomas and hyperparathyroidism.The case p...

A 20 year of man with cerebral palsy (spastic diplegia and mild learning difficulties) initially presented to the neurologists with a 4 month history of deterioration in mobility and new difficulties in speech, swallowing and incontinence of urine. New proximal muscle weakness, dyskinesia and ataxia were noted bilaterally in all limbs, Myoclonic jerks and absence seizures were also seen. His swallowing deteriorated to the point where 'PEG' feeding was necessary. Exhaustive neu...

Mediastinal location of a functional parathyroid adenoma is a rare but a well recognised entity and Tc-99M sestamibi scan is an established imaging technique for the succesful localization of such tissues with a sensitivity and specificity of more than 90%. Here we report an unusual case of primary hyperparathyroidism presenting with a 3-cm mediastinal mass with no evidence of abnormal uptake of the isotope and subsequent resolution of the mass on further imaging.<p class...

A 77 year old lady was referred by her GP after she was found to have a 6x5x5 cm diameter solid mass in the right adrenal gland on ultrasound scan. The mass showed significant internal vascularity on colour doppler and the radiologist felt it could be aphaeochromocytoma. She had a long history of hypertension which her GP had been finding difficult to control over the past 2 years.Type 2 diabetes was diagnosed 2 years ago and she...

Adrenocortical carcinoma is extremely rare and accounts for 0.05–2% of all malignant neoplasms with an estimated incidence of 0.5–2% per million people per year. Feminising adrenal carcinoma is even rarer. We submit such a rare case presenting with gynaecomastia.A 50 year old man presented with a year history of increasing bilateral gynaecomastia. He had no problems with his sexual function. Initial investigations by the GP showed low testoster...

Since 1994, after initial outpatient review (OPD) for thyrotoxicosis, we have minimised OPD attendance and provided shared-care advice to primary care physicians on thyroid function tests (TFT) and anti-thyroid drug (ATD) and levothyroxine (T4) dose titration using our electronic patient record (EPR). Using EPR data we analysed treatment (Rx) choice, effectiveness and outcomes, classifying patients as autoimmune (+ve TPO or other Graves’ features), nodular, mix...